The main objective of this study was to compare the chemical composition and antiproliferative effect of extracts and essential oils from three narrow-leaved lavender (Lavandula angustifolia Mill.) cultivars. Essential oil composition were compared and the drug concentration providing the highest yield of extract was determined. The obtained lavender extracts and essential oils were in vitro tested in HeLa, MCF7, CCRF-CEM and G-361 tumour lines and non-malignant control BJ human foreskin fibroblasts to measure cell viability. Furthermore, some of the extracts were investigated in terms of their inhibitory activity on Na+/K+-ATPase measured via inorganic phosphate concentration determined.

Scientific field

Medicine

Country

Czech Republic

Contestants

Tomáš Heger